Deep sequencing of RSV from an adult challenge study and from naturally infected infants reveals heterogeneous diversification dynamics

As RNA virus mutation occurs during replication within host cells, we hypothesized that viral evolution during acute infections in healthy hosts reflects host immune pressure. We therefore investigated the within-host diversification of human respiratory syncytial virus (RSV), a highly prevalent cau...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Lau, Jessica W., Kim, Young-In, Murphy, Ryan, Newman, Ruchi, Yang, Xiao, Zody, Michael, DeVincenzo, John, Grad, Yonatan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580249/
https://ncbi.nlm.nih.gov/pubmed/28779686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.07.017
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