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The miR‐15 family reinforces the transition from proliferation to differentiation in pre‐B cells

Precursor B lymphocytes expand upon expression of a pre‐B cell receptor (pre‐BCR), but then transit into a resting state in which immunoglobulin light chain gene recombination is initiated. This bi‐phasic sequence is orchestrated by the IL‐7 receptor (IL‐7R) and pre‐BCR signaling, respectively, but...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Lindner, Silke E, Lohmüller, Michael, Kotkamp, Bianka, Schuler, Fabian, Knust, Zeynep, Villunger, Andreas, Herzog, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579393/
https://ncbi.nlm.nih.gov/pubmed/28705801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643735
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