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Recombination at subtelomeres is regulated by physical distance, double‐strand break resection and chromatin status

Homologous recombination (HR) is a conserved mechanism that repairs broken chromosomes via intact homologous sequences. How different genomic, chromatin and subnuclear contexts influence HR efficiency and outcome is poorly understood. We developed an assay to assess HR outcome by gene conversion (GC...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Batté, Amandine, Brocas, Clémentine, Bordelet, Hélène, Hocher, Antoine, Ruault, Myriam, Adjiri, Adouda, Taddei, Angela, Dubrana, Karine
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579382/
https://ncbi.nlm.nih.gov/pubmed/28754657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796631
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