Loss of the canonical spindle orientation function in the Pins/LGN homolog AGS3

In many cell types, mitotic spindle orientation relies on the canonical “LGN complex” composed of Pins/LGN, Mud/NuMA, and Gα(i) subunits. Membrane localization of this complex recruits motor force generators that pull on astral microtubules to orient the spindle. Drosophila Pins shares highly conser...

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Detalles Bibliográficos
Publicado en:EMBO Rep
Autores principales: Saadaoui, Mehdi, Konno, Daijiro, Loulier, Karine, Goiame, Rosette, Jadhav, Vaibhav, Mapelli, Marina, Matsuzaki, Fumio, Morin, Xavier
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
Materias:
Scientific Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579374/
https://ncbi.nlm.nih.gov/pubmed/28684399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643048
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