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Loss of the canonical spindle orientation function in the Pins/LGN homolog AGS3
In many cell types, mitotic spindle orientation relies on the canonical “LGN complex” composed of Pins/LGN, Mud/NuMA, and Gα(i) subunits. Membrane localization of this complex recruits motor force generators that pull on astral microtubules to orient the spindle. Drosophila Pins shares highly conser...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579374/ https://ncbi.nlm.nih.gov/pubmed/28684399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643048 |
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