APP mouse models for Alzheimer's disease preclinical studies

Animal models of human diseases that accurately recapitulate clinical pathology are indispensable for understanding molecular mechanisms and advancing preclinical studies. The Alzheimer's disease (AD) research community has historically used first‐generation transgenic (Tg) mouse models that ov...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Sasaguri, Hiroki, Nilsson, Per, Hashimoto, Shoko, Nagata, Kenichi, Saito, Takashi, De Strooper, Bart, Hardy, John, Vassar, Robert, Winblad, Bengt, Saido, Takaomi C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579350/
https://ncbi.nlm.nih.gov/pubmed/28768718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797397
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