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Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors
Patients with malignant peripheral nerve sheath tumor (MPNST), a rare soft tissue cancer associated with loss of the tumor suppressor neurofibromin (NF1), have poor prognosis and typically respond poorly to adjuvant therapy. We evaluated the effect of 299 clinical and investigational compounds on se...
Kaydedildi:
Yayımlandı: | Mol Oncol |
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Asıl Yazarlar: | , , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2017
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579334/ https://ncbi.nlm.nih.gov/pubmed/28556483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12086 |
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