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Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis

Interferon γ (IFN-γ) induces an inflammatory response and apoptotic cell death. Rheumatoid arthritis (RA) is a systemic inflammatory disease associated with increased levels of inflammatory mediators, including tumour necrosis factor α (TNF-α) and T helper (Th) 17 cells, and downregulation of apopto...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Lee, Seung Hoon, Kwon, Ji ye, Kim, Se-Young, Jung, KyoungAh, Cho, Mi-La
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579272/
https://ncbi.nlm.nih.gov/pubmed/28860618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09767-0
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