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Ssu72 attenuates autoimmune arthritis via targeting of STAT3 signaling and Th17 activation
Signal transducer and activator of transcription 3 (STAT3) orchestrates the differentiation of several cell types, including interleukin-17 (IL-17)-releasing Th17 cells. Dysregulation of Th17 cells results in chronic inflammatory responses. Ssu72 is a C-terminal domain phosphatase required for trans...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5511296/ https://ncbi.nlm.nih.gov/pubmed/28710354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05421-x |
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