Efavirenz decreases etonogestrel exposure: a pharmacokinetic evaluation of implantable contraception with antiretroviral therapy

OBJECTIVES: The primary objective of this study was to characterize the pharmacokinetics of etonogestrel (ENG) released from a contraceptive implant in Ugandan women living with HIV who were receiving efavirenz (EFV)- or nevirapine (NVP)-based antiretroviral therapy (ART), compared to ART-naïve wome...

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Pubblicato in:AIDS
Autori principali: CHAPPELL, Catherine A., LAMORDE, Mohammed, NAKALEMA, Shadia, CHEN, Beatrice A., MACKLINE, Hope, RIDDLER, Sharon A., COHN, Susan E., DARIN, Kristin M., ACHILLES, Sharon L., SCARSI, Kimberly K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578871/
https://ncbi.nlm.nih.gov/pubmed/28692531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001591
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