The Safety, Immunogenicity and Acceptability of Inactivated Influenza Vaccine Delivered by Microneedle Patch: a Randomized, Partially Blind, Placebo-Controlled Phase 1 Trial

BACKGROUND: Microneedle patches provide an alternative to conventional needle-and-syringe immunization, and potentially offer improved immunogenicity, simplicity, cost-effectiveness, acceptability and safety. We describe safety, immunogenicity and acceptability of the first-in-human study on single,...

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Publicado en:Lancet
Autores principales: Rouphael, Nadine G, Paine, Michele, Mosley, Regina, Henry, Sebastien, McAllister, Devin V, Kalluri, Haripriya, Pewin, Winston, Frew, Paula M, Yu, Tianwei, Thornburg, Natalie J., Kabbani, Sarah, Lai, Lilin, Vassilieva, Elena V, Skountzou, Ioanna, Compans, Richard W, Mulligan, Mark J, Prausnitz, Mark R
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578828/
https://ncbi.nlm.nih.gov/pubmed/28666680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(17)30575-5
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