The Safety, Immunogenicity and Acceptability of Inactivated Influenza Vaccine Delivered by Microneedle Patch: a Randomized, Partially Blind, Placebo-Controlled Phase 1 Trial

BACKGROUND: Microneedle patches provide an alternative to conventional needle-and-syringe immunization, and potentially offer improved immunogenicity, simplicity, cost-effectiveness, acceptability and safety. We describe safety, immunogenicity and acceptability of the first-in-human study on single,...

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Detalhes bibliográficos
Publicado no:Lancet
Main Authors: Rouphael, Nadine G, Paine, Michele, Mosley, Regina, Henry, Sebastien, McAllister, Devin V, Kalluri, Haripriya, Pewin, Winston, Frew, Paula M, Yu, Tianwei, Thornburg, Natalie J., Kabbani, Sarah, Lai, Lilin, Vassilieva, Elena V, Skountzou, Ioanna, Compans, Richard W, Mulligan, Mark J, Prausnitz, Mark R
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578828/
https://ncbi.nlm.nih.gov/pubmed/28666680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(17)30575-5
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