Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases

Gcn5-related N-acetyltransferases (GNATs) are found in all kingdoms of life and catalyze important acyl transfer reactions in diverse cellular processes. While many 3D structures of GNATs have been determined, most do not contain acceptor substrates in their active sites. To expand upon existing cry...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS Lett
Egile Nagusiak: Reidl, Cory, Majorek, Karolina A, Dang, Joseph, Tran, David, Jew, Kristen, Law, Melissa, Payne, Yasmine, Minor, Wladek, Becker, Daniel P., Kuhn, Misty L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578807/
https://ncbi.nlm.nih.gov/pubmed/28703494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12753
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