Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases

Gcn5-related N-acetyltransferases (GNATs) are found in all kingdoms of life and catalyze important acyl transfer reactions in diverse cellular processes. While many 3D structures of GNATs have been determined, most do not contain acceptor substrates in their active sites. To expand upon existing cry...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Principais autores: Reidl, Cory, Majorek, Karolina A, Dang, Joseph, Tran, David, Jew, Kristen, Law, Melissa, Payne, Yasmine, Minor, Wladek, Becker, Daniel P., Kuhn, Misty L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578807/
https://ncbi.nlm.nih.gov/pubmed/28703494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12753
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