TSS-Seq analysis of low pH-induced gene expression in intercalated cells in the renal collecting duct

Metabolic acidosis often results from chronic kidney disease; in turn, metabolic acidosis accelerates the progression of kidney injury. The mechanisms for how acidosis facilitates kidney injury are not fully understood. To investigate whether low pH directly affects the expression of genes controlli...

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Bibliographic Details
Published in:PLoS One
Main Authors: Izumi, Yuichiro, Inoue, Hideki, Nakayama, Yushi, Eguchi, Koji, Yasuoka, Yukiko, Matsuo, Naomi, Nonoguchi, Hiroshi, Kakizoe, Yutaka, Kuwabara, Takashige, Mukoyama, Masashi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578634/
https://ncbi.nlm.nih.gov/pubmed/28859164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184185
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