The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix.

Lignende værker

• The first twelve amino acids (less than half of the pre-sequence) of an imported mitochondrial protein can direct mouse cytosolic dihydrofolate reductase into the yeast mitochondrial matrix.
  af: Hurt, E C, et al.
  Udgivet: (1985)
• Sequences from a prokaryotic genome or the mouse dihydrofolate reductase gene can restore the import of a truncated precursor protein into yeast mitochondria.
  af: Baker, A, et al.
  Udgivet: (1987)
• Binding of mitochondrial precursor proteins to the cytoplasmic domains of the import receptors Tom70 and Tom20 is determined by cytoplasmic chaperones.
  af: Komiya, T, et al.
  Udgivet: (1997)
• A purified precursor polypeptide requires a cytosolic protein fraction for import into mitochondria.
  af: Ohta, S, et al.
  Udgivet: (1984)
• A yeast mutant temperature-sensitive for mitochondrial assembly is deficient in a mitochondrial protease activity that cleaves imported precursor polypeptides.
  af: Yaffe, M P, et al.
  Udgivet: (1985)