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Sequences from a prokaryotic genome or the mouse dihydrofolate reductase gene can restore the import of a truncated precursor protein into yeast mitochondria.

Sequences that are capable of restoring mitochondrial targeting to a truncated yeast cytochrome c oxidase subunit IV presequence are encoded within the genome of Escherichia coli and within the gene for a higher eukaryotic cytosolic protein, mouse dihydrofolate reductase. These sequences, which rese...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Baker, A, Schatz, G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3033634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.10.3117
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