Leptin Receptor Gene Variant rs11804091 Is Associated with BMI and Insulin Resistance in Spanish Female Obese Children: A Case-Control Study

Leptin is an endocrine hormone that has a critical role in body weight homoeostasis and mediates its effects via the leptin receptor (LEPR). Common polymorphisms in the genes coding leptin receptors have been associated with metabolic abnormalities. We assessed the association of 28 LEPR polymorphis...

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Pubblicato in:Int J Mol Sci
Autori principali: Olza, Josune, Rupérez, Azahara I., Gil-Campos, Mercedes, Leis, Rosaura, Cañete, Ramón, Tojo, Rafael, Gil, Ángel, Aguilera, Concepción M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578080/
https://ncbi.nlm.nih.gov/pubmed/28771179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081690
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