Effects of X-chromosome Tenomodulin Genetic Variants on Obesity in a Children’s Cohort and Implications of the Gene in Adipocyte Metabolism

Tenomodulin (TNMD) is a type II transmembrane glycoprotein that has been recently linked to obesity, and it is highly expressed in obese adipose tissue. Several sex-dependent associations have been observed between single-nucleotide polymorphisms (SNPs) of the TNMD gene, which is located in the X-ch...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ruiz-Ojeda, Francisco Javier, Anguita-Ruiz, Augusto, Rupérez, Azahara I., Gomez-Llorente, Carolina, Olza, Josune, Vázquez-Cobela, Rocío, Gil-Campos, Mercedes, Bueno, Gloria, Leis, Rosaura, Cañete, Ramón, Moreno, Luis A., Gil, Angel, Aguilera, Concepcion Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408551/
https://ncbi.nlm.nih.gov/pubmed/30850679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40482-0
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