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Intramitochondrial Ascorbic Acid Enhances the Formation of Mitochondrial Superoxide Induced by Peroxynitrite via a Ca(2+)-Independent Mechanism
Exposure of U937 cells to peroxynitrite promotes mitochondrial superoxide formation via a mechanism dependent on both inhibition of complex III and increased mitochondrial Ca(2+) accumulation. Otherwise inactive concentrations of the oxidant produced the same maximal effects in the presence of eithe...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5578076/ https://ncbi.nlm.nih.gov/pubmed/28767071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081686 |
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