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Unrearranged immunoglobulin lambda variable region is transcribed in kappa-producing myelomas.

Most cell lines which secrete immunoglobulin kappa chains retain their lambda light chain genes in the germline configuration. We report that the lambda variable (V lambda) region is nevertheless transcribed in such kappa-secreting cells at a steady-state level of 1-10 RNA molecules per cell. These...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Picard, D, Schaffner, W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1984
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC557807/
https://ncbi.nlm.nih.gov/pubmed/6098463
Tagiau: Ychwanegu Tag
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