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Unrearranged immunoglobulin lambda variable region is transcribed in kappa-producing myelomas.

Most cell lines which secrete immunoglobulin kappa chains retain their lambda light chain genes in the germline configuration. We report that the lambda variable (V lambda) region is nevertheless transcribed in such kappa-secreting cells at a steady-state level of 1-10 RNA molecules per cell. These...

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Bibliografische gegevens
Hoofdauteurs: Picard, D, Schaffner, W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1984
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC557807/
https://ncbi.nlm.nih.gov/pubmed/6098463
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