Activation of immunoglobulin mu gene expression involves stepwise demethylation.

In an attempt to identify stages of mu gene activation subsequent to VHDHJH assembly, we investigated two pre-B cell lines (A1 and A8) that have both alleles of the JH locus rearranged but do not make mu polypeptides. The block in A1 reflects incorrect VHDHJH assembly on both alleles. In A8, althoug...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Gerondakis, S, Boyd, A, Bernard, O, Webb, E, Adams, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557805/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6098461/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb02248.x
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