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Somatic rearrangements forming active immunoglobulin mu genes in B and T lymphoid cell lines.

We have cloned an active gene for an immunoglobulin mu heavy (H) chain, bearing the variable (VH), joining (JH), and constant (C mu) sequences expressed in the IgM-secreting mouse plasmacytoma HPC-76. The mu gene was formed by somatic recombination between a VH gene and one of several JH genes, whic...

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Bibliographic Details
Main Authors: Cory, S, Adams, J M, Kemp, D J
Format: Artigo
Language:Inglês
Published: 1980
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC349965/
https://ncbi.nlm.nih.gov/pubmed/6776532
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