Inhibition of proteolytic cleavage of the hemagglutinin of influenza virus by the calcium-specific ionophore A23187.

At calcium-specific ionophore A23187 concentrations of approximately 0.25 microM [which still allow assembly and release of fowl plague virus (FPV) particles] post-translational proteolytic cleavage of the viral hemagglutinin precursor HA into the fragments HA1 and HA2 is inhibited. The resulting vi...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Klenk, H D, Garten, W, Rott, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6441705/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb02231.x
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