Addition of nucleoside analogues to peg-IFNα-2a enhances virological response in chronic hepatitis B patients without early response to peg-IFNα-2a: a randomized controlled trial

BACKGROUND: Current treatments for chronic hepatitis B (CHB) include pegylated interferon alpha (PEG-IFN-α) which is an immune modulator, and nucleos(t)ide analogs (NAs) which directly inhibit HBV DNA polymerase. With the limited efficacy of PEG-IFN-α and prolonged treatment periods associated with...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Xu, Yan, Wang, Xu, Liu, Zhenhua, Zhou, Changyu, Qi, Wenqian, Jiao, Jian, Yu, Fan, Guo, Honghua, Zhao, Ping, Wang, Jiangbin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577782/
https://ncbi.nlm.nih.gov/pubmed/28854883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-017-0657-y
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