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(89)Zr-DFO-AMG102 Immuno-PET to Determine Local Hepatocyte Growth Factor Protein Levels in Tumors for Enhanced Patient Selection
The hepatocyte growth factor (HGF) binding antibody rilotumumab (AMG102) was modified for use as a (89)Zr-based immuno-PET imaging agent to noninvasively determine the local levels of HGF protein in tumors. Because recent clinical trials of HGF-targeting therapies have been largely unsuccessful in s...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Nucl Med |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Society of Nuclear Medicine
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577625/ https://ncbi.nlm.nih.gov/pubmed/28280216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.116.187310 |
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