Muscle carnitine availability plays a central role in regulating fuel metabolism in the rodent

KEY POINTS: Meldonium inhibits endogenous carnitine synthesis and tissue uptake, and accelerates urinary carnitine excretion, although the impact of meldonium‐mediated muscle carnitine depletion on whole‐body fuel selection, and muscle fuel metabolism and its molecular regulation is under‐investigat...

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Bibliographische Detailangaben
Veröffentlicht in:J Physiol
Hauptverfasser: Porter, Craig, Constantin‐Teodosiu, Dumitru, Constantin, Despina, Leighton, Brendan, Poucher, Simon M., Greenhaff, Paul L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Muscle
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577538/
https://ncbi.nlm.nih.gov/pubmed/28605113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274415
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