Acetyl group availability influences phosphocreatine degradation even during intense muscle contraction

We previously established that activation of the pyruvate dehydrogenase complex (PDC) using dichloroacetate (DCA) reduced the reliance on substrate-level phosphorylation (SLP) at the onset of exercise, with normal and reduced blood flow. PDC activation also reduced fatigue development during contrac...

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Detalhes bibliográficos
Main Authors: Timmons, James A, Constantin-Teodosiu, Dumitru, Poucher, Simon M, Greenhaff, Paul L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665386/
https://ncbi.nlm.nih.gov/pubmed/15498812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.069419
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