Accumulation of H/ACA snoRNPs depends on the integrity of the conserved central domain of the RNA-binding protein Nhp2p

Box H/ACA small nucleolar ribonucleoprotein particles (H/ACA snoRNPs) play key roles in the synthesis of eukaryotic ribosomes. How box H/ACA snoRNPs are assembled remains unknown. Here we show that yeast Nhp2p, a core component of these particles, directly binds RNA. In vitro, Nhp2p interacts with h...

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Bibliografske podrobnosti

izdano v:	Nucleic Acids Res
Principais autores:	Henras, Anthony, Dez, Christophe, Noaillac-Depeyre, Jacqueline, Henry, Yves, Caizergues-Ferrer, Michèle
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2001
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11433018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.13.2733
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