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The role of ubiquitin-dependent segregase p97 (VCP or Cdc48) in chromatin dynamics after DNA double strand breaks

DNA double strand breaks (DSBs) are the most cytotoxic DNA lesions and, if not repaired, lead to chromosomal rearrangement, genomic instability and cell death. Cells have evolved a complex network of DNA repair and signalling molecules which promptly detect and repair DSBs, commonly known as the DNA...

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Dades bibliogràfiques
Publicat a:Philos Trans R Soc Lond B Biol Sci
Autors principals: Torrecilla, Ignacio, Oehler, Judith, Ramadan, Kristijan
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577460/
https://ncbi.nlm.nih.gov/pubmed/28847819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0282
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