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Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates

Periodontitis is a chronic inflammatory disease associated with overactivation of the complement system. Recent preclinical studies suggest that host-modulation therapies may contribute to effective treatment of human periodontitis, which may lead to loss of teeth and function if untreated. We previ...

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發表在:Mol Ther Methods Clin Dev
Main Authors: Kajikawa, Tetsuhiro, Briones, Ruel A., Resuello, Ranillo R.G., Tuplano, Joel V., Reis, Edimara S., Hajishengallis, Evlambia, Garcia, Cristina A.G., Yancopoulou, Despina, Lambris, John D., Hajishengallis, George
格式: Artigo
語言:Inglês
出版: American Society of Gene & Cell Therapy 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577415/
https://ncbi.nlm.nih.gov/pubmed/28879212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.08.001
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