Co-encapsulation and co-transplantation of mesenchymal stem cells reduces pericapsular fibrosis and improves encapsulated islet survival and function when allografted

Pericapsular fibrotic overgrowth (PFO) is associated with poor survival of encapsulated islets. A strategy to combat PFO is the use of mesenchymal stem cells (MSC). MSC have anti-inflammatory properties and their potential can be enhanced by stimulation with proinflammatory cytokines. This study inv...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vaithilingam, Vijayaganapathy, Evans, Margaret D. M., Lewy, Denise M., Bean, Penelope A., Bal, Sumeet, Tuch, Bernard E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577272/
https://ncbi.nlm.nih.gov/pubmed/28855611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10359-1
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