The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes

Two-pore channels (TPCs) are localized in endo-lysosomal compartments and assumed to play an important role for vesicular fusion and endosomal trafficking. Recently, it has been shown that both TPC1 and 2 were required for host cell entry and pathogenicity of Ebola viruses. Here, we investigate the...

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Publicat a:Sci Rep
Autors principals: Castonguay, Jan, Orth, Joachim H. C., Müller, Thomas, Sleman, Faten, Grimm, Christian, Wahl-Schott, Christian, Biel, Martin, Mallmann, Robert Theodor, Bildl, Wolfgang, Schulte, Uwe, Klugbauer, Norbert
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577145/
https://ncbi.nlm.nih.gov/pubmed/28855648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10607-4
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