Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins

Axons contain a smooth tubular endoplasmic reticulum (ER) network that is thought to be continuous with ER throughout the neuron; the mechanisms that form this axonal network are unknown. Mutations affecting reticulon or REEP proteins, with intramembrane hairpin domains that model ER membranes, caus...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Yalçın, Belgin, Zhao, Lu, Stofanko, Martin, O'Sullivan, Niamh C, Kang, Zi Han, Roost, Annika, Thomas, Matthew R, Zaessinger, Sophie, Blard, Olivier, Patto, Alex L, Sohail, Anood, Baena, Valentina, Terasaki, Mark, O'Kane, Cahir J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576921/
https://ncbi.nlm.nih.gov/pubmed/28742022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23882
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