Caricamento...

Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens

The malaria parasite Plasmodium falciparum and related apicomplexan pathogens contain an essential plastid organelle, the apicoplast, which is a key anti-parasitic target. Derived from secondary endosymbiosis, the apicoplast depends on novel, but largely cryptic, mechanisms for protein/lipid import...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Amberg-Johnson, Katherine, Hari, Sanjay B, Ganesan, Suresh M, Lorenzi, Hernan A, Sauer, Robert T, Niles, Jacquin C, Yeh, Ellen
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576918/
https://ncbi.nlm.nih.gov/pubmed/28826494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29865
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !