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Early cytoplasmic uncoating is associated with infectivity of HIV-1

After fusion, HIV delivers its conical capsid into the cytoplasm. To release the contained reverse-transcribing viral genome, the capsid must disassemble in a process termed uncoating. Defining the kinetics, dynamics, and cellular location of uncoating of virions leading to infection has been confou...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mamede, João I., Cianci, Gianguido C., Anderson, Meegan R., Hope, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576815/
https://ncbi.nlm.nih.gov/pubmed/28784755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706245114
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