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Arc restores juvenile plasticity in adult mouse visual cortex

The molecular basis for the decline in experience-dependent neural plasticity over age remains poorly understood. In visual cortex, the robust plasticity induced in juvenile mice by brief monocular deprivation during the critical period is abrogated by genetic deletion of Arc, an activity-dependent...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jenks, Kyle R., Kim, Taekeun, Pastuzyn, Elissa D., Okuno, Hiroyuki, Taibi, Andrew V., Bito, Haruhiko, Bear, Mark F., Shepherd, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576785/
https://ncbi.nlm.nih.gov/pubmed/28790183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700866114
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