Arc restores juvenile plasticity in adult mouse visual cortex

The molecular basis for the decline in experience-dependent neural plasticity over age remains poorly understood. In visual cortex, the robust plasticity induced in juvenile mice by brief monocular deprivation during the critical period is abrogated by genetic deletion of Arc, an activity-dependent...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Jenks, Kyle R., Kim, Taekeun, Pastuzyn, Elissa D., Okuno, Hiroyuki, Taibi, Andrew V., Bito, Haruhiko, Bear, Mark F., Shepherd, Jason D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576785/
https://ncbi.nlm.nih.gov/pubmed/28790183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700866114
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