Transfer of in vitro-expanded naïve T cells after lymphodepletion enhances antitumor immunity through the induction of polyclonal antitumor effector T cells

The adoptive transfer of effector T cells combined with lymphodepletion has demonstrated promising antitumor effects in mice and humans, although the availability of tumor-specific T cells is limited. We and others have also demonstrated that the transfer of polyclonal naïve T cells induces tumor-sp...

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發表在:PLoS One
Main Authors: Tanaka, Tomohiro, Watanabe, Satoshi, Takahashi, Miho, Sato, Ko, Saida, Yu, Baba, Junko, Arita, Masashi, Sato, Miyuki, Ohtsubo, Aya, Shoji, Satoshi, Nozaki, Koichiro, Ichikawa, Kosuke, Kondo, Rie, Aoki, Nobumasa, Ohshima, Yasuyoshi, Sakagami, Takuro, Abe, Tetsuya, Moro, Hiroshi, Koya, Toshiyuki, Tanaka, Junta, Kagamu, Hiroshi, Yoshizawa, Hirohisa, Kikuchi, Toshiaki
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576657/
https://ncbi.nlm.nih.gov/pubmed/28854279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183976
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