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Glucocorticoid Receptor ChIP-Seq Identifies PLCD1 as a KLF15 Target that Represses Airway Smooth Muscle Hypertrophy

Glucocorticoids exert important therapeutic effects on airway smooth muscle (ASM), yet few direct targets of glucocorticoid signaling in ASM have been definitively identified. Here, we show that the transcription factor, Krüppel-like factor 15 (KLF15), is directly induced by glucocorticoids in prima...

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Detalles Bibliográficos
Publicado en:Am J Respir Cell Mol Biol
Main Authors: Sasse, Sarah K., Kadiyala, Vineela, Danhorn, Thomas, Panettieri, Reynold A., Phang, Tzu L., Gerber, Anthony N.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576583/
https://ncbi.nlm.nih.gov/pubmed/28375666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0357OC
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