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Glucocorticoid Receptor ChIP-Seq Identifies PLCD1 as a KLF15 Target that Represses Airway Smooth Muscle Hypertrophy

Glucocorticoids exert important therapeutic effects on airway smooth muscle (ASM), yet few direct targets of glucocorticoid signaling in ASM have been definitively identified. Here, we show that the transcription factor, Krüppel-like factor 15 (KLF15), is directly induced by glucocorticoids in prima...

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Bibliografische gegevens
Gepubliceerd in:Am J Respir Cell Mol Biol
Hoofdauteurs: Sasse, Sarah K., Kadiyala, Vineela, Danhorn, Thomas, Panettieri, Reynold A., Phang, Tzu L., Gerber, Anthony N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576583/
https://ncbi.nlm.nih.gov/pubmed/28375666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0357OC
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