EGFR copy number alterations in primary tumors, metastatic lymph nodes, and recurrent and multiple primary tumors in oral cavity squamous cell carcinoma

BACKGROUND: The EGFR and downstream signaling pathways play an important role in tumorigenesis in oral squamous cell carcinoma (OSCC). Gene copy number alteration is one mechanism for overexpressing the EGFR protein and was also demonstrated to be related to lymph node metastasis, tumor invasiveness...

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Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Huang, Shiang-Fu, Chien, Huei-Tzu, Cheng, Sou-De, Chuang, Wen-Yu, Liao, Chun-Ta, Wang, Hung-Ming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576106/
https://ncbi.nlm.nih.gov/pubmed/28854970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3586-9
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