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High affinity epidermal growth factor receptors on the surface of A431 cells have restricted lateral diffusion.

Rhodamine-labelled epidermal growth factor (Rh-EGF) was shown to bind to A431 cells grown at low density both to a small number of high affinity receptors (KD = 2.8 X 10(-10) M; fraction of total binding sites approximately 0.12) and also to a large number of low affinity receptors (KD = 4 X 10(-9)...

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Bibliographic Details
Published in:EMBO J
Main Authors: Rees, A R, Gregoriou, M, Johnson, P, Garland, P B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1984
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6090128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb02057.x
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