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Enhanced inflammasome activity in systemic lupus erythematosus is mediated via type I interferon upregulation of interferon regulatory factor 1

OBJECTIVE: The inflammasome complex is a driver of organ damage in systemic lupus erythematosus (SLE). While type I interferons (IFNs) are well established as mediators of SLE pathogenesis, their role in inflammasome activation in SLE has not been assessed. Thus, we examined type I IFNs as regulator...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Arthritis Rheumatol
मुख्य लेखकों: Liu, Jianhua, Berthier, Celine C., Kahlenberg, J. Michelle
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575977/
https://ncbi.nlm.nih.gov/pubmed/28564495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40166
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