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Identification of cis-regulatory mutations generating de novo edges in personalized cancer gene regulatory networks
The identification of functional non-coding mutations is a key challenge in the field of genomics. Here we introduce μ-cisTarget to filter, annotate and prioritize cis-regulatory mutations based on their putative effect on the underlying “personal” gene regulatory network. We validated μ-cisTarget b...
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| Vydáno v: | Genome Med |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5575942/ https://ncbi.nlm.nih.gov/pubmed/28854983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0464-7 |
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