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A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP‐2
Cholesterol synthesis is regulated by the transcription factor sterol regulatory element binding protein 2 (SREBP‐2) and its target gene 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMGCR), which is the rate‐limiting enzyme in cholesterol synthesis. Cyclic adenosine monophosphate–responsive elem...
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| Udgivet i: | Hepatology |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5575482/ https://ncbi.nlm.nih.gov/pubmed/28395113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29206 |
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