A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP‐2

Cholesterol synthesis is regulated by the transcription factor sterol regulatory element binding protein 2 (SREBP‐2) and its target gene 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMGCR), which is the rate‐limiting enzyme in cholesterol synthesis. Cyclic adenosine monophosphate–responsive elem...

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Vydáno v:Hepatology
Hlavní autoři: Li, Yujie, Song, Yongfeng, Zhao, Meng, Guo, Yanjing, Yu, Chunxiao, Chen, Wenbin, Shao, Shanshan, Xu, Chao, Zhou, Xinli, Zhao, Lifang, Zhang, Zhenhai, Bo, Tao, Xia, Yu, Proud, Christopher G., Wang, Xuemin, Wang, Li, Zhao, Jiajun, Gao, Ling
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575482/
https://ncbi.nlm.nih.gov/pubmed/28395113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29206
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