PD‐L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation

The expression of PD‐L1 in breast cancer is associated with estrogen receptor negativity, chemoresistance and epithelial‐to‐mesenchymal transition (EMT), all of which are common features of a highly tumorigenic subpopulation of cancer cells termed cancer stem cells (CSCs). Hitherto, the expression a...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Almozyan, Sheema, Colak, Dilek, Mansour, Fatmah, Alaiya, Ayodele, Al‐Harazi, Olfat, Qattan, Amal, Al‐Mohanna, Falah, Al‐Alwan, Monther, Ghebeh, Hazem
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Molecular Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575465/
https://ncbi.nlm.nih.gov/pubmed/28614911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30834
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