Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: Significance in claudin-low breast cancer cells

BACKGROUND: The T-cell inhibitory molecule PD-L1 (B7-H1, CD274) is expressed on tumor cells of a subset of breast cancer patients. However, the mechanism that regulates PD-L1 expression in this group of patients is still not well-identified. METHODS: We have used loss and gain of function gene manip...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Alsuliman, Abdullah, Colak, Dilek, Al-Harazi, Olfat, Fitwi, Hanaa, Tulbah, Asma, Al-Tweigeri, Taher, Al-Alwan, Monther, Ghebeh, Hazem
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527106/
https://ncbi.nlm.nih.gov/pubmed/26245467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0421-2
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