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The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival.

The survival of cultured chick sympathetic neurons and the outgrowth of neurites were stimulated by the basement membrane protein laminin coated onto polyornithine culture substrates. The survival-potentiating activity was dependent on the presence of nerve growth factor. Both effects of laminin cou...

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Vydáno v:EMBO J
Hlavní autoři: Edgar, D, Timpl, R, Thoenen, H
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1984
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6745238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb01997.x
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