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The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival.

The survival of cultured chick sympathetic neurons and the outgrowth of neurites were stimulated by the basement membrane protein laminin coated onto polyornithine culture substrates. The survival-potentiating activity was dependent on the presence of nerve growth factor. Both effects of laminin cou...

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Bibliografiska uppgifter
Huvudupphovsmän: Edgar, D, Timpl, R, Thoenen, H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1984
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC557545/
https://ncbi.nlm.nih.gov/pubmed/6745238
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